首页 | 期刊简介 | 编委会 | 投稿要求 | 化学品管理信息动态 | 学术会议 | 专辑 | 毒理学测试技术设备 | 订购本刊 | 联系我们 | English version

任东凯,苏红巧,刘芃岩,韦荣国,等. 全氟烷基磺酸盐(PFOS)及其替代品对两栖类胚胎的发育毒性[J]. 生态毒理学报, 2012, 7(5): 561-564
全氟烷基磺酸盐(PFOS)及其替代品对两栖类胚胎的发育毒性
Developmental Toxicity of Perfluorooctane Sulfonate (PFOS) and Its Substitutes to Amphibian Embryos
投稿时间:2012-06-30  修订日期:2012-09-08
DOI:
中文关键词:  PFOS  替代品  非洲爪蟾  黑斑蛙  发育毒性
英文关键词:PFOS  substitutes  Xenopus laevis  Rana nigromaculata  developmental toxicity
基金项目:“863”计划课题(2010AA 065105)和环保公益专项(201109048)
作者单位
任东凯 1. 河北大学化学与环境科学学院保定 071002
2. 中国科学院生态环境研究中心
环境化学和生态毒理学国家重点实验室北京 100085 
苏红巧 中国科学院生态环境研究中心环境化学和生态毒理学国家重点实验室北京 100085 
刘芃岩 河北大学化学与环境科学学院保定 071002 
韦荣国 中国科学院生态环境研究中心环境化学和生态毒理学国家重点实验室北京 100085 
秦占芬 中国科学院生态环境研究中心环境化学和生态毒理学国家重点实验室北京 100085 
摘要点击次数: 2809
全文下载次数: 2156
中文摘要:
      用非洲爪蟾胚胎致畸实验和黑斑蛙胚胎发育毒性实验,比较研究了PFOS及其4种替代品对两栖动物胚胎的发育毒性。结果发现,用调聚法合成的织物三防整理剂和50%的全氟丁基有机铵盐阳离子表面活性剂同PFOS一样对非洲爪蟾胚胎有明显毒性,且织物三防整理剂和表面活性剂的毒性强于PFOS;电解氟化法合成的C4织物及C6织物三防整理剂(以下简称C4及C6织物三防整理剂)对非洲爪蟾胚胎没有明显毒性。与非洲爪蟾不同,PFOS和4种替代品对黑斑蛙胚胎没有明显毒性。结果显示,从生物安全性的角度分析,C4和C6织物三防整理剂可作为PFOS的替代品使用,而织物三防整理剂和表面活性剂的毒性比PFOS大,作为PFOS替代品使用需要慎重考虑。
              
AuthorAffiliation
Ren Dongkai1. College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China
2. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
Su HongqiaoState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
Liu PengyanCollege of Chemistry and Environmental Science, Hebei University, Baoding 071002, China
Wei RongguoState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
Qin ZhanfenState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
英文摘要:
      In this study, the developmental toxicity of perfluorooctane sulfonate (PFOS) and its four substitutes on Xenopus laevis embryos and Rana nigromaculata embryos studied comparatively. It was found that tri-fabric finishing agent synthetized using telomerization method (tri-fabric finishing agent) and 50% perfluorobutyl organic ammonium salt cationic surfactant (50% cationic surfactants) as well as PFOS had obvious toxicity to X. laevis embryos. Moreover, the toxicity of tri-fabric finishing agent and 50% cationic surfactant was significantly higher than that of PFOS. C4 and C6 tri-proof finishing agent (C4 and C6) synthetized by electrolysis fluorination method were not toxic to X. laevis embryos. To R. nigromaculata embryos, PFOS and four substitutes had no obvious toxicity. In term of biological safety, these results show that C4 and C6 might be used as the substitutes for PFOS, while tri-fabric finishing agent and 50% cationic surfactant should be considered carefully.
查看全文  查看/发表评论  下载PDF阅读器
关闭

您是第5793568位访问者   京ICP备 09058833 号

主办单位:中国科学院生态环境研究中心     单位地址:北京市海淀区双清路18号

 服务热线:010-62941072       传真:010-62923563       邮编:100085    Email: stdlxb@rcees.ac.cn

    本系统由北京勤云科技发展有限公司设计

0463美女美女3764美女美女ktv