纳米材料对环境抗生素抗性基因污染扩散影响的研究进展
Influence of Nanomaterials on the Spread of Environmental Antibiotic Resistance Genes: A Review
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摘要: 抗生素抗性基因(antibiotic resistance genes,ARGs)的环境扩散严重威胁了人类健康和生态安全。除抗生素滥用所产生的选择性压力以外，其他环境物质也能影响ARGs的传播。而纳米材料的广泛应用使其不可避免地在环境中扩散并进而影响ARGs的环境分布。因此，笔者综述了近年来纳米材料影响ARGs污染扩散的研究，并探讨了纳米材料对ARGs传播的影响机制，旨在深入理解ARGs的环境扩散行为，为ARGs环境控制及纳米材料非毒性环境效应的评估提供理论和技术支持。Abstract: The spread of antibiotic resistance genes (ARGs) in the environment poses serious threats to human health and ecological safety. Besides selective pressure caused by antibiotic abuse, other environmental substances can also affect spread of ARGs. The widely used nanomaterials inevitably spread in the environment, affecting distribution of ARGs. To give a comprehensive understanding of spread behavior of ARGs in environment, this paper reviews the recent studies about the influence of nanomaterials on the spread of ARGs and discusses the spread mechanisms of ARGs in the presence of nanomaterials. This will provide a theoretical and technical support for risk control of environmental ARGs and assessment of non-toxic effect of nanomaterials in environment.
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