首页 | 期刊简介 | 编委会 | 投稿要求 | 化学品管理信息动态 | 学术会议 | 专辑 | 毒理学测试技术设备 | 订购本刊 | 联系我们 | English version

余丽琴,赵高峰,冯敏,李昆,等. 典型氯酚类化合物对水生生物的毒性研究进展[J]. 生态毒理学报, 2013, 8(5): 658-670
典型氯酚类化合物对水生生物的毒性研究进展
Toxicological Effects of Typical Chlorophenol Chemicals on Aquatic Organisms
投稿时间:2013-01-05  修订日期:2013-03-14
DOI:10.7524/AJE.1673-5897.20130105001
中文关键词:  2,4-二氯酚  2,4,6-三氯酚  五氯酚  水生生物  毒理
英文关键词:2,4-dichlorophenol  2,4,6-trichlorophenol  pentachlorophenol  aquatic organisms  toxicology
基金项目:国家自然科学基金(21247007);国家水体污染控制与治理科技重大项目(2012ZX07203-006);中国博士后基金(2013M530054);中国水利水电科学研究院院专项(环集 1339)
作者单位
余丽琴 中国水利水电科学研究院北京 100038 
赵高峰 中国水利水电科学研究院北京 100038 
冯敏 中国水利水电科学研究院北京 100038 
李昆 中国水利水电科学研究院北京 100038 
文武 中国水利水电科学研究院北京 100038 
张盼伟 中国水利水电科学研究院北京 100038 
邹晓雯 中国水利水电科学研究院北京 100038 
周怀东 中国水利水电科学研究院北京 100038 
摘要点击次数: 2888
全文下载次数: 2182
中文摘要:
      氯酚类化合物(CPs)是一类广泛存在于水环境中的有机污染物。这类化合物具有环境稳定性、生物累积性和生物毒性,因而其在水环境中的生态毒理效应一直是人们关注的焦点。在水体中存在最普遍的酚类化合物主要有2,4-二氯酚(2,4-DCP),2,4,6-三氯酚(2,4,6-TCP)和五氯酚(PCP)。本文对近几年来这3种典型氯酚类化合物的水生态毒理学研究进行了总结,主要包括它们对水生生物的急性毒性、氧化损伤、发育毒性、内分泌干扰、遗传毒性、致癌性、免疫毒性、细胞毒性以及复合毒性的效应和机制,同时对目前存在的问题和进一步的研究方向进行了讨论和展望。
                       
AuthorAffiliation
Yu LiqinChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Zhao GaofengChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Feng MinChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Li KunChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Wen WuChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Zhang PanweiChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Zou XiaowenChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
Zhou HuaidongChina Institute of Water Resources and Hydropower Research, Beijing 100038, China
英文摘要:
      Chlorophenol chemicals (CPs) are widespread environmental contaminants. They are persistent and bioaccumulative, and can affect wildlife and human health. Among CPs, 2,4-dichlorophenol (2,4-DCP), 2,4,6-trichlorophenol (2,4,6-TCP) and pentachlorophenol (PCP) were extensively used and could be detected in most waters. Here we reviewed the environmental behavior of the three typical CPs and their toxicity to aquatic organisms, including acute toxicity, developmental toxicity, oxidative stress, endocrine-disruption, genotoxicity, carcinogenicity, immunotoxicity, cytotoxicity and joint-effect toxicity. Furthermore, molecular techniques, such as toxicomics were used for elucidating the mechanisms of action of CPs, with which some sensitive and effective biomarkers had been found. We also discussed research gaps and perspectives that warrant further investigations.
查看全文  查看/发表评论  下载PDF阅读器
关闭

您是第5264137位访问者   京ICP备 09058833 号

主办单位:中国科学院生态环境研究中心     单位地址:北京市海淀区双清路18号

 服务热线:010-62941072       传真:010-62923563       邮编:100085    Email: stdlxb@rcees.ac.cn

    本系统由北京勤云科技发展有限公司设计

0463美女美女3764美女美女ktv