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刘敏,殷浩文,陈晓倩,李康,等. PFOS潜在替代品全氟丁基磺酸钾对不同营养水平水生生物的毒性[J]. 生态毒理学报, 2013, 8(5): 714-721
PFOS潜在替代品全氟丁基磺酸钾对不同营养水平水生生物的毒性
Toxicities of Potassium Perfluorobutane Sulfonate as Potential Alternative of Perfluorooctane Sulfonate to Multi-Species of Different Trophic Levels
投稿时间:2012-07-10  修订日期:2012-10-26
DOI:10.7524/AJE.1673-5897.20120710003
中文关键词:  全氟丁基磺酸钾(PFBSK)  水生毒性  PFOS  毒性比较
英文关键词:PFBSK  aquatic toxicity  PFOS  toxicity comparison
基金项目:"863"计划课题(2010 AA065105)
作者单位
刘敏 上海市检测中心生物与安全实验室上海 201203 
殷浩文 上海市检测中心生物与安全实验室上海 201203 
陈晓倩 上海市检测中心生物与安全实验室上海 201203 
李康 上海市检测中心生物与安全实验室上海 201203 
杨婧 上海市检测中心生物与安全实验室上海 201203 
张京佶 上海市检测中心生物与安全实验室上海 201203 
贾丽娟 上海市检测中心生物与安全实验室上海 201203 
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中文摘要:
      全氟丁基磺酸钾(PFBSK)作为全氟辛基磺酸(PFOS)潜在的替代品,极易溶于水,主要存在于水体中,因而其水生毒性的研究十分重要。采用OECD 201、OECD 202、OECD 203和OECD 211标准试验方法,研究了PFBSK对羊角月牙藻(Pseudokirchneriella subcapitata)、大型溞(Daphnia magna)和中国本土鱼种稀有鮈鲫(Gobiocypris rarus)的急性毒性效应以及对大型溞繁殖的影响。组合多终点急慢性水生生物毒性结果:PFBSK的急性毒性终点均大于100 mg·L-1,大型溞繁殖试验的无观察效应浓度(NOEC)为571 mg·L-1,最低可观察效应浓度(LOEC)为981 mg·L-1。按GHS分类导则,PFBSK未表现出急性毒性和慢性毒性。与之相比,PFOS则对水生生物表现出毒性,黑头软口鲦(Pimephales promelas)为最敏感物种,其96 h-LC50为4.7 mg·L-1;大型溞繁殖试验的NOEC为12 mg·L-1。按GHS分类导则,属于中等毒性物质。可见,PFBSK较PFOS水生毒性明显降低。
                    
AuthorAffiliation
Liu MinBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Yin HaowenBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Chen XiaoqianBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Li KangBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Yang JingBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Zhang JingjiBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
Jia LijuanBioassay and Safety Assessment Laboratory, Shanghai Academy of Public Measurement, Shanghai 201203, China
英文摘要:
      Potassium perfluorobutane sulfonate (PFBSK) as potential alternative of perfluorooctane sulfonate (PFOS), has high water solubility and is found mainly in waters. Therefore, it is important to investigate the aquatic toxicity of PFBSK. The aquatic acute toxicity tests were performed on the green algae (Pseudokirchneriella subcapitata), the invertebrates (Daphnia magna) and Chinese indigenous fish (Gobiocypris rarus) according to OECD guidelines 201, 202 and 203. Daphnia magna reproduction test was performed according to OECD 211. The results showed that PFBSK exhibited no obvious acute and chronic toxicity according to GHS standards since all of endpoints of acute toxicity test are higher than 100 mg·L-1 and the NOEC and LOEC of 21-day reproduction test for Daphnia magna are 571 mg·L-1 and 981 mg·L-1. In comparison with PFBSK, fathead minnow (Pimephales promelas) was the most susceptible freshwater fish species to PFOSK in acute test with 96 h-LC50 of 4.7 mg·L-1. NOEC of PFOSK for D. magna 21-day reproduction test was 12 mg·L-1. According to GHS standards, PFOS is moderate toxic to aquatic life. In conclusion, aquatic toxicity of PFBS was much lower than PFOS.
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